William Miller was an engraver and illustrator in the 1800s, known familiarly as “the Scotch Quaker.” He created wonderfully detailed plates of, well, nearly anything that required a technical illustration – lighthouses under construction, botanical specimens, tapeworms or, as here, parts of the human body. Many of the engravings in the marvelous Wikimedia Commons collection [1] from whence this piece came were done “after” someone else. Evidently, a person would draw a picture of a flower or piece of algae under a microscope, then hand it to William to make it work for printing.
This haunting skull, though, is William Miller after W. Miller. It’s part of a series that includes these delicate glimpses inside the fragile white dome [2].
You can read more about Miller (and his favorite illustrators) over here, at Wikipedia [3].