The Telegraph provides insight into the genuine pain of a broken heart:
Psychologists at the University of California, Los Angeles say the human body has a gene which connects physical pain sensitivity with social pain sensitivity.
The findings back the common theory that rejection ‘hurts’ by showing that a gene regulating the body’s most potent painkillers – mu-opioids – is involved in socially painful experiences too.
Their study indicates that a variation in the mu-opioid receptor gene (OPRM1), often associated with physical pain, is related to how much social pain a person feels in response to social rejection.
Co-author Baldwin Way said: “These findings suggest that the feeling of being given the cold shoulder by a romantic interest or not being picked for a schoolyard game of basketball may arise from the same circuits.”